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Treatment centers in Greenville, SC

๐Ÿ“˜ Read our complete guide: Treatment Guide for Greenville โ€” insurance, free options, MAT, and more.

Finding the right treatment center in Greenville can feel overwhelming. We've compiled 9 facilities in the area to help you compare options based on the care they provide, not just their marketing.

9 facilities in Greenville, SC

Treatment options in Greenville, SC include substance abuse treatment, mental health services, medical detoxification and medication-assisted treatment (MAT) across 9 verified facilities. Payment options include private insurance, Medicaid, Medicare, sliding scale payment. Browse listings below and call to check availability.

Need help choosing? Read our guide to choosing a treatment center or call SAMHSA at 1-800-662-4357 for free referrals.

Crossroads Treatment Centers
Greenville, SC
Not yet verified
OutpatientMATTelehealth
Relapse PreventionPregnant Women
Accepts: Private insurance, Medicaid, Medicare, Self-pay
Call 800-805-6989 Is this your center? Claim your listing
Greenville Metro Treatment Center
Greenville, SC
Not yet verified
OutpatientMATTelehealth
CBTMotivational InterviewingRelapse Prevention
Accepts: Private insurance, Medicaid, Medicare, Self-pay
Call 864-234-7952 x15505 Is this your center? Claim your listing
Life Line Services LLC
Greenville, SC
Not yet verified
OutpatientDetoxMATTelehealth
Dual DiagnosisTraumaCBT
Accepts: Private insurance, Self-pay
Call 864-775-5509 Is this your center? Claim your listing
Pavillon
Greenville, SC
Not yet verified
OutpatientIOPTelehealth
Dual DiagnosisTraumaCBT
Accepts: Private insurance, Self-pay
Call 864-241-6688 Is this your center? Claim your listing
Phoenix Center
Greenville, SC
Not yet verified
OutpatientIOPMATTelehealth
TraumaCBT12-Step
Accepts: Private insurance, Medicaid, Self-pay, Sliding scale
Call 864-467-3790 Is this your center? Claim your listing
Phoenix Center
Greenville, SC
Not yet verified
Hospital InpatientDetoxMAT
TraumaCBT12-Step
Accepts: Private insurance, Medicaid, Self-pay, Sliding scale
Call 864-467-3770 Is this your center? Claim your listing
Phoenix Center
Greenville, SC
Not yet verified
ResidentialMATTransitional Housing
TraumaCBT12-Step
Accepts: Private insurance, Medicaid, Self-pay, Sliding scale
Call 864-467-3881 Is this your center? Claim your listing
Greater Greenville Mental Health
Greenville, SC
Not yet verified
OutpatientTelehealth
Dual DiagnosisTraumaCBT
Accepts: Private insurance, Medicaid, Medicare
Call 864-241-1040 Is this your center? Claim your listing
Marshall I Pickens Hospital
Greenville, SC
Not yet verified
Hospital InpatientOutpatientTelehealth
Dual DiagnosisCBTMotivational Interviewing
Accepts: Private insurance, Medicaid, Medicare
Call 864-455-1285 Is this your center? Claim your listing

How to choose a treatment center in Greenville

Before contacting any facility, verify they're licensed in South Carolina, ask about their treatment approach, confirm they accept your insurance, and request to speak with clinical staff. Our complete guide walks you through every question to ask.

Helpful guides

How to choose a treatment center: Complete checklist โ†’ What does insurance cover for treatment? โ†’ IOP vs PHP vs residential: Which level of care? โ†’ How much does rehab cost in 2026? โ†’

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