Substance guides
Alcohol and cancer risk: What the science says
Alcohol is a Group 1 carcinogen (confirmed to cause cancer in humans) classified by the International Agency for Research on Cancer. This is the same category as tobacco and asbestos.
Linked cancers
Breast cancer (even moderate drinking increases risk). Liver cancer. Colorectal cancer. Esophageal cancer. Head and neck cancers (mouth, throat, larynx). Stomach cancer.
How much increases risk
There is no safe level of alcohol consumption for cancer risk. Risk increases with any amount and rises with quantity. However, the absolute risk increase from moderate drinking is small. Heavy drinking substantially increases risk.
The mechanism
Alcohol is metabolized to acetaldehyde, a toxic compound that damages DNA. It also increases estrogen levels (breast cancer link), impairs nutrient absorption, and causes inflammation.
The nuance
While any alcohol increases cancer risk, the absolute risk from moderate drinking is small for most cancers. The decision to drink should weigh this against other health effects and personal risk factors.
Frequently asked questions
Does alcohol cause cancer?
How much alcohol increases cancer risk?
Does quitting reduce cancer risk?
Disclaimer: Informational only. Not medical advice. SAMHSA: 1-800-662-4357.