Substance guides
How to safely dispose of prescription drugs
Published December 10, 2024 · 6 min read · Updated April 2026
Reviewed for accuracy by licensed clinical professionals.
Unused medications in your home are a diversion risk. Safe disposal prevents misuse.
DEA take-back programs
Biannual DEA National Prescription Drug Take Back events. Year-round drop-off locations at many pharmacies and police stations. DEATakeBack.com for locations.
At-home disposal
FDA recommends flushing certain opioids if take-back is not available. For other medications: mix with coffee grounds or kitty litter, seal in container, remove labels, place in household trash. Mail-back programs available from some pharmacies.
Why it matters
Over 50% of prescription opioid misuse begins with someone else's prescription. Securing and disposing of unused medications prevents diversion.
Frequently asked questions
Where can I dispose of prescription drugs?
DEA take-back events, pharmacy drop-off locations, and police stations. DEATakeBack.com for locations near you.
Can I flush prescription drugs?
FDA recommends flushing certain opioids if take-back is unavailable. Other medications should be mixed with inedible materials and discarded.
Why should I dispose of unused medications?
Over 50% of prescription opioid misuse begins with someone else's prescription. Unused medications are a diversion risk.
Disclaimer: Informational only. Not medical advice. SAMHSA: 1-800-662-4357.