How do I get my loved one into treatment?

Start with a calm, caring conversation expressing specific concerns. Offer to help research treatment options. Consider the CRAFT method (Community Reinforcement and Family Training), which has a 64-74% success rate. A professional intervention is another option if they refuse.

Should I do an intervention?

Professional interventions have an 80-90% success rate in getting the person to accept treatment. Consider an intervention when your loved one denies the problem, has refused repeated suggestions to get help, and consequences are escalating.

Modern treatments

Psychedelic-assisted therapy: Where to find legal clinical programs in 2026

Published October 24, 2025 · 10 min read · Updated April 2026

Last medically reviewed: April 2026

Reviewed for accuracy by licensed clinical professionals. Editorial process.

Psychedelic-assisted therapy has moved from the fringes to the forefront of psychiatric research. Here is where things stand in 2026 and how to access legal programs.

What's currently available

Ketamine and esketamine (Spravato) are the only psychedelic-related treatments currently available through standard medical channels. Ketamine is used off-label for treatment-resistant depression at ketamine clinics nationwide. Esketamine (Spravato) is FDA-approved for treatment-resistant depression and administered as a nasal spray in certified healthcare settings. Both require in-office administration with monitoring.

MDMA-assisted therapy

MDMA-assisted therapy for PTSD has shown remarkable efficacy in clinical trials, with approximately 67% of participants no longer meeting PTSD diagnostic criteria after treatment. The FDA regulatory pathway has been complex, and the current status of MDMA approval should be verified with the FDA directly, as this landscape continues to evolve.

Psilocybin therapy

Oregon's regulated psilocybin program allows supervised psilocybin sessions at licensed service centers. Colorado has also established a regulatory framework for psychedelic therapy. These are state-level programs, not FDA-approved treatments. Clinical trials for psilocybin-assisted therapy for depression, anxiety, and addiction continue at major research universities.

How to access treatment safely

For ketamine and esketamine: Ask your psychiatrist for a referral, or search for ketamine clinics in your area. Ensure the clinic is physician-supervised. For clinical trials: Search clinicaltrials.gov for active psychedelic therapy trials recruiting participants. For Oregon and Colorado programs: Visit the respective state regulatory websites for lists of licensed service centers. Be extremely cautious of unregulated "ceremonies" or underground providers — these lack the clinical safeguards that make psychedelic therapy safe and effective.