Recovery & aftercare

Trazodone in recovery: A safe sleep medication

Published July 26, 2025 · 6 min read · Updated April 2026

Reviewed for accuracy by licensed clinical professionals.

Trazodone is one of the most commonly prescribed sleep medications in addiction treatment because it is effective for insomnia with no abuse potential.

How it works

Trazodone is technically an antidepressant but at low doses (25-100mg) its primary effect is sedation. It works through serotonin and histamine receptor activity.

Why it is preferred in recovery

Non-addictive with no abuse potential. Does not produce tolerance (continues working long-term). Does not interact with MAT medications. Does not produce the cognitive impairment of benzodiazepines. Does not risk the complex sleep behaviors of Z-drugs.

Practical details

Typical dose for sleep: 50-100mg at bedtime. Side effects: morning grogginess (start at 25mg), dry mouth, and rarely priapism in men. Takes effect within 30-60 minutes. Can be used long-term safely.

Authoritative sources

This article references guidelines from: SAMHSA · NIDA · ASAM

Frequently asked questions

Is trazodone safe in recovery?

Yes. Trazodone has no abuse potential and is one of the most commonly prescribed sleep aids in addiction treatment.

Is trazodone addictive?

No. Trazodone does not produce dependence, tolerance, or withdrawal.

How much trazodone for sleep?

Typically 50-100mg at bedtime. Start at 25mg to minimize morning grogginess.

Disclaimer: Informational only. Not medical advice. SAMHSA: 1-800-662-4357.