Substance guides

What are overdose prevention centers?

Published February 1, 2025 · 7 min read · Updated April 2026
Reviewed for accuracy by licensed clinical professionals.

Facilities where people use pre-obtained substances under medical supervision. Zero deaths at any site worldwide. Increase treatment entry. Do not increase drug use.

Authoritative sources

This article references guidelines from: NIDA · SAMHSA · CDC

Frequently asked questions

How do I find help?
Call SAMHSA at 1-800-662-4357 or search our directory.
Does insurance cover this?
Most insurance covers substance abuse treatment.
Is treatment effective?
Yes. Evidence-based treatment produces significant improvement.

Disclaimer: Informational only. Not medical advice. SAMHSA: 1-800-662-4357.